BDBM50340888 (4-amino-2-(4-chlorophenylamino)thiazol-5-yl)(3-nitrophenyl)methanone::CHEMBL1614763::{4-amino-2-[(4-chlorophenyl)amino]-1,3-thiazol-5-yl}(3-nitrophenyl)methanone

SMILES Nc1nc(Nc2ccc(Cl)cc2)sc1C(=O)c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=YQRVBHMYUSGXHL-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340888   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50340888((4-amino-2-(4-chlorophenylamino)thiazol-5-yl)(3-ni...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK5/P25 using full length tau as substrate by colorimetric ELISAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50340888((4-amino-2-(4-chlorophenylamino)thiazol-5-yl)(3-ni...)
Affinity DataIC50:  750nMAssay Description:Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into peptide PKTPKKAKKL substrate after 45 mins by scintillation counterMore data for this Ligand-Target Pair