BDBM50341332 CHEMBL1766350::rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(benzyloxy)benzyl)-1H-1,2,3-triazol-4-yl)methylamino]cyclohexane-1,2,3,4,5-pentaol

SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(Cc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)nn2)[C@@H](O)[C@@H]1O

InChI Key InChIKey=OIFZDLBPIABAJR-YCHSXSCJSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50341332   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataKi:  50nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of yeast alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataIC50:  50nMpH: 5.2Assay Description:Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 5.2 after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of alpha-galactosidase from coffee beansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine liver beta-galactosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataIC50:  60nMpH: 7.4Assay Description:Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 7.4 after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable alpha-glucosidase Os06g0675700(Oryza sativa subsp. japonica)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rice alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed