BDBM50342065 (S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(5-(pyridin-2-yl)oxazol-2-yl)methanone::CHEMBL1765831

SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1ncc(o1)-c1ccccn1

InChI Key InChIKey=PTLQKIGLQLGNRL-IBGZPJMESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342065   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342065((S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli using [14C]oleamide as substrate assessed as oleic acid formation by Dixon plot anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342065((S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342065((S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed