BDBM50346422 10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenothiazine-2-carbonitrile::CHEMBL251940::PROPERICIAZINE::periciazine

SMILES OC1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C#N)CC1

InChI Key InChIKey=LUALIOATIOESLM-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50346422   

TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenoth...)
Affinity DataKi:  4.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenoth...)
Affinity DataKi:  160nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenoth...)
Affinity DataKi:  220nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenoth...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50346422(10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenoth...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]mibolerone from rat androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenoth...)
Affinity DataKi:  3.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346422(10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenoth...)
Affinity DataIC50:  230nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346422(10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenoth...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of bovine erythrocyte AChE using acetylthiocholine iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed