BDBM50352551 CHEMBL1821759

SMILES CC(C)n1cc(cn1)-c1cnc(N)c(OC(C)c2c(Cl)ccc(F)c2Cl)c1

InChI Key InChIKey=JHPYCETZLQWNOY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352551   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352551(CHEMBL1821759)
Affinity DataKi:  37nMAssay Description:Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352551(CHEMBL1821759)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed