BDBM50353047 CHEMBL1822526

SMILES COc1cc(ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1)N1CCN(C[C@@H](C)O)CC1

InChI Key InChIKey=PYEVUJXYLLDVLP-HXUWFJFHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50353047   

TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353047(CHEMBL1822526)
Affinity DataIC50:  80nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353047(CHEMBL1822526)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353047(CHEMBL1822526)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant ALK assessed as phosphorylated product using PLC-gamma/GST substrate by modified ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed