BDBM50359530 CHEMBL1927151

SMILES Clc1ccc(CN2CCCn3c(C2)c2c(cc3=O)[nH]n(-c3ccccc3Cl)c2=O)cc1

InChI Key InChIKey=WMIICUNBBWCKDS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359530   

TargetNADPH oxidase 1(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359530(CHEMBL1927151)
Affinity DataKi:  95nMAssay Description:Antagonist activity at human NOX1 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359530(CHEMBL1927151)
Affinity DataKi:  103nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 5(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359530(CHEMBL1927151)
Affinity DataKi:  585nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359530(CHEMBL1927151)
Affinity DataKi:  1.26E+3nMAssay Description:Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed