BDBM50360767 CHEMBL1934493

SMILES COc1ccc(cc1)N1C(=S)S\C(=C/c2ccc(O)c(Br)c2)C1=O

InChI Key InChIKey=HEFKAUYVLSGPGC-DHDCSXOGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50360767   

Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50360767(CHEMBL1934493)
Affinity DataIC50:  6nMAssay Description:Inhibition of 17beta-HSD3 in human testes homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50360767(CHEMBL1934493)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Mus musculus)
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50360767(CHEMBL1934493)
Affinity DataIC50:  40nMAssay Description:Inhibition of 17beta-HSD3 in mouse testes homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50360767(CHEMBL1934493)
Affinity DataIC50:  14nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cells assessed as conversion of 4-androstene-3,17-dione to testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed