BDBM50363398 CHEMBL1946171

SMILES Cn1c(Nc2ccc(cc2)C(F)(F)F)nc2ccc(Oc3ccnc(c3)-c3c[nH]c(n3)C(F)(F)F)cc12

InChI Key InChIKey=HRCJMYWMDPFSHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363398   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50363398(CHEMBL1946171)
Affinity DataIC50:  3nMAssay Description:Inhibition of wild-type B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50363398(CHEMBL1946171)
Affinity DataIC50:  30nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50363398(CHEMBL1946171)
Affinity DataIC50:  3nMAssay Description:Inhibition of C-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed