BDBM50373099 CHEMBL99553::NE-10575

SMILES C[n+]1cccc(CC(O)(P(O)(O)=O)P(O)(O)=O)c1

InChI Key InChIKey=BBNRLGQPSIXFHZ-UHFFFAOYSA-O

Data  2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50373099   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)
Affinity DataKi:  3.90nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)
Affinity DataKi:  177nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)
Affinity DataIC50:  19.6nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Aquifex aeolicus)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Aquifex aeolicus IspH expressed in Escherichia coli BL21 (DE3) using HMBPP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)
Affinity DataIC50:  1.71E+3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair