BDBM50376011 CHEMBL270754

SMILES CNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12

InChI Key InChIKey=HFLGPAUKVFOIOT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50376011   

TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376011(CHEMBL270754)
Affinity DataIC50:  110nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376011(CHEMBL270754)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376011(CHEMBL270754)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376011(CHEMBL270754)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376011(CHEMBL270754)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376011(CHEMBL270754)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50376011(CHEMBL270754)
Affinity DataIC50:  700nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed