BDBM50380547 CHEMBL2019053

SMILES Oc1cc2oc(cc(=O)c2cc1O)C(=O)NCCCCCCCCCCNc1c2CCCCc2nc2cc(Cl)ccc12

InChI Key InChIKey=VNWJCXLTKRADKP-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50380547   

TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380547(CHEMBL2019053)
Affinity DataKi:  3.99E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380547(CHEMBL2019053)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380547(CHEMBL2019053)
Affinity DataIC50:  18nMAssay Description:Inhibition of bovine erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380547(CHEMBL2019053)
Affinity DataIC50:  95nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380547(CHEMBL2019053)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380547(CHEMBL2019053)
Affinity DataIC50:  28nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed