BDBM50384608 CHEMBL2036801::US9744172, Compound UNC00000471A

SMILES NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCc4ccccc4)nc23)CC1

InChI Key InChIKey=GPXJRVLKUZJOES-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50384608   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384608(CHEMBL2036801 | US9744172, Compound UNC00000471A)
Affinity DataIC50:  38nMAssay Description:Inhibition of Axl using KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50384608(CHEMBL2036801 | US9744172, Compound UNC00000471A)
Affinity DataIC50: <10nMAssay Description:The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50384608(CHEMBL2036801 | US9744172, Compound UNC00000471A)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384608(CHEMBL2036801 | US9744172, Compound UNC00000471A)
Affinity DataIC50:  75nMAssay Description:Inhibition of Tyro3 using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed