BDBM50384610 CHEMBL2036803::US9744172, Compound UNC00000472A

SMILES NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCCc4ccccc4)nc23)CC1

InChI Key InChIKey=QJLMOARFSPIREY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50384610   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384610(CHEMBL2036803 | US9744172, Compound UNC00000472A)
Affinity DataIC50:  41nMAssay Description:Inhibition of Axl using KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50384610(CHEMBL2036803 | US9744172, Compound UNC00000472A)
Affinity DataIC50:  55nMAssay Description:The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50384610(CHEMBL2036803 | US9744172, Compound UNC00000472A)
Affinity DataIC50:  13nMAssay Description:Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384610(CHEMBL2036803 | US9744172, Compound UNC00000472A)
Affinity DataIC50:  18nMAssay Description:Inhibition of Tyro3 using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed