BDBM50386957 CHEMBL2048822

SMILES Cc1cn2cc(CC(=O)N3CCC4(CN(Cc5ccc(cc5)-c5ncccn5)C4)CC3)nc2s1

InChI Key InChIKey=PBNZRGKDARJEKD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50386957   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386957(CHEMBL2048822)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human GHS-R1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced europium-labeled GTP binding by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386957(CHEMBL2048822)
Affinity DataIC50:  90nMAssay Description:Displacement of [125I]Ghrelin from human GHS-R1a expressed in HEK293 cells after 8 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed