BDBM50387063 CHEMBL2047040
SMILES CC(C)c1cccc(CNC[C@@H](O)[C@@H]2COC\C=C\C[C@H](NC(=O)c3cc(cc(c3)C(=O)N2)N(C)S(C)(=O)=O)c2ccccc2)c1
InChI Key InChIKey=XYJDOUBLYLOJJL-YNYOQIOBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50387063
Affinity DataIC50: 400nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair