BDBM50392215 CHEMBL2153161

SMILES CC(C)CS(=O)(=O)C[C@H](NC(=O)c1ccccc1)C(=O)N(C)N(C)C#N

InChI Key InChIKey=UGAZRSHSXNNYTK-HNNXBMFYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50392215   

TargetCathepsin S(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392215(CHEMBL2153161)
Affinity DataKi:  0.550nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Val-Arg-pNA as substrate after 80 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392215(CHEMBL2153161)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human cathepsin K using Z-Leu-Arg-AMC as substrate after 80 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392215(CHEMBL2153161)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA as substrate after 80 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392215(CHEMBL2153161)
Affinity DataKi:  15nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-pNA as substrate after 80 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin F(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392215(CHEMBL2153161)
Affinity DataKi:  21nMAssay Description:Inhibition of human recombinant cathepsin F using Z-Phe-Arg-AMC as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed