BDBM50395569 CHEMBL2165119::UNC10099975::US9156822, 3 or UNC9975
SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4n3)CC2)c1Cl
InChI Key InChIKey=JQSRFMXTGAVHIR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50395569
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.10nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.20nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting methodMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 2.60nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 7.40nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 11nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 29nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 99nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 178nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 513nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.04E+3nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataEC50: 3.30nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataEC50: 1.80E+3nMAssay Description:Cell Culture: Chinese Hamster Ovary (CHO) cells stably expressing the hD2L dopamine receptor (Urban et al., Neuropsychopharmacology 32:67 (2007)) wer...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataEC50: 13nMpH: 7.4Assay Description:HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at D2L receptor in human HTLA cells assessed as beta arrestin recruitment at 6 uM after 18 hrs by luminescence assayMore data for this Ligand-Target Pair