BDBM50400183 Purpuro (Ligand 1)::XANTHOPURPURIN
SMILES Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1
InChI Key InChIKey=WPWWKBNOXTZDQJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50400183
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Binding affinity to Bcl-2 after 30 mins by florescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 2.27E+3nMAssay Description:Binding affinity to Mcl-1 after 30 mins by florescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [172-327](Homo sapiens (Human))
Dalian University Of Technology
Dalian University Of Technology
Affinity DataKd: 1.35E+6nMpH: 8.0 T: 2°CAssay Description:ITC experiments were carried out using iTC200 (Microcal LLC, Northampton, MA, USA) with each of the compounds 1-6 and Mcl-1 protein. The heat of rea...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 50400183
CellInduced myeloid leukemia cell differentiation protein Mcl-1 (aa 172-327)(Homo sapiens (Human))
Dalian University Of Technology
Dalian University Of Technology
ITC DataΔG°: -3.94kcal/mole −TΔS°: -2.49kcal/mole ΔH°: -1.45kcal/mole logk: 778
pH: 8.0 T: 25.00°C
pH: 8.0 T: 25.00°C