BDBM50400519 CHEMBL2204941
SMILES Fc1ccc(cc1)-c1c[nH]c(n1)[C@H]1Cc2c([nH]c3ccccc23)[C@H](N1)C1CCOCC1
InChI Key InChIKey=FRWHMBLUCGXEQQ-FYYLOGMGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50400519
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 377nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 377nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to human somatostatin receptor type 3More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]SS-28 from human SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 5.70nMAssay Description:Antagonist activity at human somatostatin receptor type 3 assessed as inhibition of cAMP levelsMore data for this Ligand-Target Pair