BDBM50402226 CHEMBL2204737

SMILES CC(C)CCNC(=O)[C@@H]1CNC[C@@H](C1)N1CC(=O)N(CC1(C)C)c1ccccc1Cl

InChI Key InChIKey=OIPASSZLGANZOF-ZWKOTPCHSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402226   

TargetRenin(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50402226(CHEMBL2204737)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of recombinant human renin using Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg as substrate incubated for 10 mins...More data for this Ligand-Target Pair
TargetRenin(Macaca fascicularis)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50402226(CHEMBL2204737)
Affinity DataIC50:  54nMAssay Description:Inhibition of renin in cynomolgus monkey plasma after 60 mins by competitive radioimmunoassayMore data for this Ligand-Target Pair