BDBM50402944 CHEMBL2206214

SMILES OCC1CCN(CC1)c1ncccc1Oc1ccc(Nc2nc3ccccc3[nH]2)cc1

InChI Key InChIKey=XGFBQNCOZRNUGL-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50402944   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50402944(CHEMBL2206214)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human PDE3A using FAM-cAMP as substrate incubated for 60 mins prior to substrate addition measured after 90 mins by IMAP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50402944(CHEMBL2206214)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50402944(CHEMBL2206214)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50402944(CHEMBL2206214)
Affinity DataIC50:  0.0970nMAssay Description:Inhibition of human PDE10A2 using FAM-cAMP as substrate incubated for 60 mins prior to substrate addition measured after 90 mins by IMAP-FRET assayMore data for this Ligand-Target Pair