BDBM50411402 CHEMBL244946

SMILES Cc1cc(-c2ccc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3c2)n(C)n1

InChI Key InChIKey=WIHMMKGUBDZGEG-UHFFFAOYSA-N

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50411402   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataKi:  1.58nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataKi:  1.58nMAssay Description:Antagonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataKi:  316nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataKi:  316nMAssay Description:Antagonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]dofetidile from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed