BDBM50413332 CHEMBL503427

SMILES CN1C(CC(CN2CCCCC2)C1=O)C#Cc1ccc2OCCc2c1

InChI Key InChIKey=BSAYMXGAHRLDCA-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50413332   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50413332(CHEMBL503427)
Affinity DataEC50:  7.94nMAssay Description:Agonist activity at human recombinant alpha7 nAChR expressed in rat GH3 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50413332(CHEMBL503427)
Affinity DataIC50:  6.31E+3nMAssay Description:Antagonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50413332(CHEMBL503427)
Affinity DataIC50:  5.01E+4nMAssay Description:Antagonist activity at human 5HT3 receptor by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50413332(CHEMBL503427)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed