BDBM50414966 CHEMBL573216

SMILES COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncn1

InChI Key InChIKey=GMCICJZIANWTML-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50414966   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414966(CHEMBL573216)
Affinity DataIC50:  120nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414966(CHEMBL573216)
Affinity DataIC50:  70.8nMAssay Description:Inhibition of wild type human ERG expressed in CHOK1 cells by whole-cell plate-based electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414966(CHEMBL573216)
Affinity DataIC50:  14.8nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed