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BDBM50418049 CL 36467::CL 39743::LEVOMEPROMAZINE::med.21724, Compound 192

SMILES: COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1

InChI Key: InChIKey=VRQVVMDWGGWHTJ-CQSZACIVSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50418049   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pleiotropic ABC efflux transporter of multiple drugs


(Saccharomyces cerevisiae S288c)
BDBM50418049
PNG
(CL 36467 | CL 39743 | LEVOMEPROMAZINE | med.21724,...)
Show SMILES COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1
Show InChI InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m1/s1
KEGG

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CHEBI
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KEGG
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 9.60E+3n/an/an/an/an/an/a



Wroclaw Medical University

Curated by ChEMBL


Assay Description
Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assay


Antimicrob Agents Chemother 53: 1516-27 (2009)


Article DOI: 10.1128/AAC.00956-08
BindingDB Entry DOI: 10.7270/Q2125TNZ
More data for this
Ligand-Target Pair
3C-like proteinase


(MERS-CoV)
BDBM50418049
PNG
(CL 36467 | CL 39743 | LEVOMEPROMAZINE | med.21724,...)
Show SMILES COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1
Show InChI InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m1/s1
PDB
MMDB

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B.MOAD
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PC cid
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PubMed
n/an/an/an/a 2.50E+3n/an/an/an/a



TBA



Assay Description
This is a review article.


Med Res Rev (2020)


BindingDB Entry DOI: 10.7270/Q2JS9ST6
More data for this
Ligand-Target Pair
Bile salt export pump


(Homo sapiens (Human))
BDBM50418049
PNG
(CL 36467 | CL 39743 | LEVOMEPROMAZINE | med.21724,...)
Show SMILES COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1
Show InChI InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m1/s1
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antibodypedia
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CHEBI
DrugBank
KEGG
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.27E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...


Drug Metab Dispos 40: 2332-41 (2012)


Article DOI: 10.1124/dmd.112.047068
BindingDB Entry DOI: 10.7270/Q2ZP488M
More data for this
Ligand-Target Pair