BDBM50419732 CHEMBL1947053

SMILES O=C(O[C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1

InChI Key InChIKey=ZVQCTZVWEBSXKK-AERCQKQUSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50419732   

TargetSoluble acetylcholine receptor(Aplysia Californica)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419732(CHEMBL1947053)
Affinity DataKi:  31.6nMAssay Description:Displacement of [3H]epibatidine from Aplysia californica acetylcholine binding protein expressed using baculoviral system after 1.5 hrs by scintillat...More data for this Ligand-Target Pair
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419732(CHEMBL1947053)
Affinity DataKi:  79.4nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine binding protein expressed using baculoviral system after 1.5 hrs by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419732(CHEMBL1947053)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]MLA from nAChR alpha7 receptor in human SH-SY5Y cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419732(CHEMBL1947053)
Affinity DataKi: >3.16E+4nMAssay Description:Displacement of [3H]epibatidine from human nAChR alpha4beta2 receptor expressed in human HEK293T cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed