BDBM50419863 CHEMBL1957475
SMILES COc1cncc(c1)-c1cccc(c1)C1(N=C(N)N2CC(F)(F)CN=C12)c1ccc(OC(F)F)cc1
InChI Key InChIKey=GIMSIOKOSRIQLD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50419863
Affinity DataIC50: 14nMAssay Description:Inhibition of BACE-1-mediated sAPPbeta production in human SH-SY5Y cells after 16 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human BACE-1 using (Eu)CEVNLDAEFK(Qsy7) as substrate preincubated for 10 mins prior substrate addition measured after 15 mins by FRET-b...More data for this Ligand-Target Pair