BDBM50420400 CHEMBL2089254

SMILES CCOc1nc(Nc2ccc(cc2)C(N)=O)cc(N)c1C#N

InChI Key InChIKey=JUNWGTQNFTURHK-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50420400   

Target40S ribosomal protein S27(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420400(CHEMBL2089254)
Affinity DataIC50:  37nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target40S ribosomal protein S27(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420400(CHEMBL2089254)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420400(CHEMBL2089254)
Affinity DataIC50:  190nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed