BDBM50422364 TRAPOXIN B

SMILES O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H]1CO1

InChI Key InChIKey=LLOKIGWPNVSDGJ-AFBVCZJXSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50422364   

TargetHistone deacetylase 2b(Zea mays)
Università

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against histone deacetylase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Mus musculus (Mouse))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration gainst Histone deacetylase 1 derived from NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50: <5nMAssay Description:Concentration required to inhibit human Histone deacetylase (HDAC) enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50: <5nMAssay Description:Inhibitory activity against histone deacetylase (HDAC) enzyme obtained from H1299 human lung carcinoma cell lysatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50:  4nMAssay Description:Concentration required to inhibit the partially purified HDAC enzyme by 50% obtained from H1299 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Università

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed