BDBM50431264 CHEMBL2333040::US9428465, 14

SMILES CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O

InChI Key InChIKey=BBZFIIUFDXKSHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50431264   

TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431264(CHEMBL2333040 | US9428465, 14)
Affinity DataIC50:  177nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431264(CHEMBL2333040 | US9428465, 14)
Affinity DataIC50:  177nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431264(CHEMBL2333040 | US9428465, 14)
Affinity DataIC50:  155nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent