BDBM50431264 CHEMBL2333040::US9428465, 14
SMILES CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O
InChI Key InChIKey=BBZFIIUFDXKSHN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50431264
Affinity DataIC50: 177nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
Affinity DataIC50: 177nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
Affinity DataIC50: 155nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair