BDBM50431812 CHEMBL2347053

SMILES [O-][N+](=O)c1ccccc1-c1n[nH]cc1C=C1C(=O)Nc2ccccc12

InChI Key InChIKey=XLYVQVWMTOLDNL-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50431812   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of PDK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of PKC alpha (unknown origin) using PIP2 as substrate after 1 hr by Kinase-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  500nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of ERK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  13nMAssay Description:Inhibition of GSK3beta (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  11nMAssay Description:Inhibition of p38alpha (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  11nMAssay Description:Inhibition of AKT1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  5.03E+3nMAssay Description:Inhibition of JNK2 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  4nMAssay Description:Inhibition of MSK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  109nMAssay Description:Inhibition of c-MET (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of SRC (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  271nMAssay Description:Inhibition of ABL (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of KDR (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PDGFRalpha (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PDGFRbeta (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  25nMAssay Description:Inhibition of FGFR3 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  12nMAssay Description:Inhibition of FGFR1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  10nMAssay Description:Inhibition of cKit (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  54nMAssay Description:Inhibition of PIM1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of LCK (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  4nMAssay Description:Inhibition of LYNA (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of p70S6K (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of Aurora B (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed