BDBM50432496 CHEMBL2349492

SMILES CC(C)Oc1cccc(c1)-c1ccc2OC(C)(C)CC3(N=C(N)N(C)C3=O)c2c1

InChI Key InChIKey=GCAUJEMXKJNLPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50432496   

TargetCathepsin D(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50432496(CHEMBL2349492)
Affinity DataIC50:  430nMAssay Description:Inhibition of human spleen cathepsin D using 5-FAM/QXL as peptide substrate after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50432496(CHEMBL2349492)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in CHO cells using biotin-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed