BDBM50432502 CHEMBL2349616

SMILES COc1ccc(cc1)-c1ccc2OC(C)(C)CC3(N=C(N)N(C)C3=O)c2c1

InChI Key InChIKey=BMASJJOJXPLURJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50432502   

TargetCathepsin D(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50432502(CHEMBL2349616)
Affinity DataIC50:  6.34E+3nMAssay Description:Inhibition of human spleen cathepsin D using 5-FAM/QXL as peptide substrate after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50432502(CHEMBL2349616)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in CHO cells using biotin-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed