BDBM50432578 CHEMBL2347165
SMILES Fc1ccc2[nH]cc(CCCNCc3ccccc3)c2c1
InChI Key InChIKey=RTLQUOXHRQJNMY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50432578
Affinity DataKi: 50nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair