BDBM50433561 CHEMBL2381408
SMILES CC(C)(C)C[C@@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@H]1CC[C@H](O)CC1
InChI Key InChIKey=IDKAKZRYYDCJDU-HBMMIIHUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50433561
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Inhibition of FAM-tagged p53-based fluorescent probe binding to human His-tagged MDM2 (1 to 118 residues) after 15 mins by fluorescence polarization ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Inhibition of FAM tagged p53-based peptide binding to recombinant human His-tagged MDM2 protein (residues 1 to 118 residues) incubated for 15 mins by...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Inhibition of PMDM6-F binding to recombinant human His-tagged MDM2 (1 to 118 residues) after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity to recombinant human His6-tagged HDM2 (1 to 118 residues) assessed as reduction in PMDM6-F binding incubated for 15 to 30 mins by fl...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity to human MDM2More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of MDM2 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKd: 2.70nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair