BDBM50433630 CHEMBL2380834
SMILES Fc1ccc(C(=O)Nc2ccc(Nc3ccnc4[nH]c(=O)c5ccccc5c34)cc2)c(c1)C(F)(F)F
InChI Key InChIKey=XISIJMIPHPQCQQ-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50433630
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataIC50: 161nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataIC50: 706nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of aurora-B in human MIAPaCa2 cells assessed as reduction of phosphorylation of histone H3More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataIC50: 575nMAssay Description:Inhibition of Fms (unknown origin)More data for this Ligand-Target Pair