BDBM50434749 CHEMBL2385586

SMILES C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1cn[nH]c1

InChI Key InChIKey=WMTXIPYJYDISKM-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50434749   

Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  82nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  59nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  55nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  55nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  129nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  38nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1B(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  3.32E+3nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  43nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed