BDBM50435764 CHEMBL2392692
SMILES CNc1nc(C)nc(n1)N1CCC(CC1)C(=O)NCc1ccc(Br)cc1OC(F)(F)F
InChI Key InChIKey=PVTFEAGMCGMRRS-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50435764
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human microsomal epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins p...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of rat soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prior ...More data for this Ligand-Target Pair
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Chieti "G. D.Annunzio
Curated by ChEMBL
University Of Chieti "G. D.Annunzio
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Chieti "G. D.Annunzio
Curated by ChEMBL
University Of Chieti "G. D.Annunzio
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prio...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Chieti "G. D.Annunzio
Curated by ChEMBL
University Of Chieti "G. D.Annunzio
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human soluble epoxide hydrolase overexpressed in HEK293F cells using EET as substrate assessed as formation of DHET incubated for 30 mi...More data for this Ligand-Target Pair