BDBM50438688 CHEMBL2414544

SMILES COc1ccc(cc1)-c1cccc2nc(Nc3ccc(cc3)N3CCN(C)CC3)nn12

InChI Key InChIKey=DPVQBIWIVWTDRV-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438688   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50438688(CHEMBL2414544)
Affinity DataKi:  0.600nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50438688(CHEMBL2414544)
Affinity DataIC50:  22nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as reduction of phosphorylated STAT5 levelMore data for this Ligand-Target Pair