BDBM50439474 CHEMBL2417906

SMILES COc1ccc(-c2ccc(cc2C(O)=O)C(=O)N[C@H](CO)C(C)(C)C)c(n1)C(=O)Nc1ccc2c(N)nccc2c1

InChI Key InChIKey=GCBXPOHPNDVIFD-HSZRJFAPSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50439474   

TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50439474(CHEMBL2417906)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human tissue plasminogen activator using spectrozyme tissue plasminogen activator as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50439474(CHEMBL2417906)
Affinity DataIC50:  7nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50439474(CHEMBL2417906)
Affinity DataIC50:  270nMAssay Description:Inhibition of human F10a using S-2222 as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50439474(CHEMBL2417906)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed