BDBM50442145 CHEMBL2441271

SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(Cc2ccccc2)cc(Nc2nc3ccc(Cl)cc3s2)n1

InChI Key InChIKey=ZRTDSOVGBJZNBQ-UAPYVXQJSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442145   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50442145(CHEMBL2441271)
Affinity DataKi:  0.316nMAssay Description:Inhibition of recombinant human FLAG-tagged ITK using biotinylated GST-SAM68 as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50442145(CHEMBL2441271)
Affinity DataKi:  251nMAssay Description:Inhibition of Aurora-B (unknown origin) using 5FAM-PKAtide as substrate after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed