BDBM50444931 CHEMBL3099765

SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cc(CO)c2cc(ccc2n1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=WCXRTEQTXGUQMQ-VWLOTQADSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444931   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444931(CHEMBL3099765)
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of B-Alexa-Fluor647 from CDK2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444931(CHEMBL3099765)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Inhibition of CDK2 (unknown origin)-cyclin A interaction preincubated for 30 mins at room temperature followed by incubation at 40 degC for 30 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444931(CHEMBL3099765)
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to CDK2 (unknown origin) at 20 to 80 degC by circular dichroism analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed