BDBM50450890 CHEMBL4206604

SMILES CC(C)n1cnc2c(Nc3ccc(cc3)N3CCN(C)CC3)nc(N[C@H]3CCN(C3)C(C)=O)nc12

InChI Key InChIKey=ACTNABQUCQIOKX-FQEVSTJZSA-N

Data  1 KI

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50450890   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi Apptec

Curated by ChEMBL

LigandBDBM50450890(CHEMBL4206604)Copy SMILESCopy InChI

Affinity DataKi:  161nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI