BDBM50453194 CHEMBL4204373

SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(CN3CCOCC3)cc2)c2ncn(C3CCCC3)c2n1

InChI Key InChIKey=SAEGVASGMTZGFI-AQYVVDRMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50453194   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453194(CHEMBL4204373)
Affinity DataIC50:  3nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) ITD mutant expressed in Sf9 insect cells using poly (Ala,Glu,L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453194(CHEMBL4204373)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human 3C cleavage site/N-terminal GST-His6 fused PDGFR alpha C-terminal fragment (Q551 to L1089 residues) harboring V561D m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453194(CHEMBL4204373)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) D835Y mutant expressed in Sf9 insect cells using poly (Ala,Glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453194(CHEMBL4204373)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant wild type human FLT3 (R571 to S993 residues) expressed in Sf9 insect cells using poly (Ala,Glu,Ly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed