BDBM50455746 CHEMBL4215249::US10829491, Compound S19

SMILES CC#CC(=O)N[C@H]1Cn2c(C1=C)c(-c1ccc(Oc3ccccc3)cc1)c1c(N)ncnc21

InChI Key InChIKey=IKIIYQAGWPMYCC-FQEVSTJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455746   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Institute Of Materia Medica, Chinese Acad

US Patent
LigandPNGBDBM50455746(CHEMBL4215249 | US10829491, Compound S19)
Affinity DataIC50: <1nMAssay Description:Poly(Glu, Tyr) 4:1 as a substrate for enzyme catalyzed reaction was diluted with potassium-free PBS (10 mM sodium phosphate buffer, 150 mM NaCl, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Institute Of Materia Medica, Chinese Acad

US Patent
LigandPNGBDBM50455746(CHEMBL4215249 | US10829491, Compound S19)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed