BDBM50463099 CHEMBL4246000

SMILES O[C@@H]1[C@@H](O)[C@H](OC(=O)c2c[nH]c3cc(F)c(c(F)c23)-c2ccc(cc2)[C@@H]2CCCCO2)O[C@@H]([C@H]1O)C(O)=O

InChI Key InChIKey=GZCJKJJWOUAGMR-WBTGXFMPSA-N

Data  1 Kd  5 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50463099   

LigandPNGBDBM50463099(CHEMBL4246000)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta2gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
LigandPNGBDBM50463099(CHEMBL4246000)
Affinity DataEC50:  332nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta1gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
LigandPNGBDBM50463099(CHEMBL4246000)
Affinity DataEC50:  59nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta1gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50463099(CHEMBL4246000)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50463099(CHEMBL4246000)
Affinity DataKd:  198nMAssay Description:Binding affinity to Bap-tagged human AMPKalpha1beta1gamma1 expressed in Escherichia coli BL21 cells by SPR analysisMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50463099(CHEMBL4246000)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair