BDBM50463197 CHEBI:50599::CHEMBL1233327

SMILES Cn1cnc(C[C@H](N)C(O)=O)c1

InChI Key InChIKey=BRMWTNUJHUMWMS-LURJTMIESA-N

Data  2 IC50

PDB links: 330 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463197   

TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50463197(CHEBI:50599 | CHEMBL1233327)
Affinity DataIC50:  1.90E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50463197(CHEBI:50599 | CHEMBL1233327)
Affinity DataIC50:  1.90E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed