BDBM50463510 CHEMBL4244382

SMILES O=c1n(cnc2ccc(cc12)-c1ccnc2ccccc12)-c1ccc(cc1)N1CCOCC1

InChI Key InChIKey=MTDJGYWCNQTZLJ-UHFFFAOYSA-N

Data  1 IC50  9 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50463510   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  54nMAssay Description:Binding affinity to partial length human KIT (I571 to D952 residues) expressed in bacterial expression system by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  1.90E+4nMAssay Description:Binding affinity to human ALK5 by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  250nMAssay Description:Binding affinity to partial length human PDGFRB (V582 to Y1009 residues) expressed in bacterial expression system by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  43nMAssay Description:Binding affinity to partial length human PDGFRA (V575 to D1002 residues) expressed in mammalian expression system by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  610nMAssay Description:Binding affinity to human ALK3 by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetActivin receptor type-1B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to human ALK4 by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  330nMAssay Description:Binding affinity to human ALK2 by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant GST-tagged human ALK2 catalytic domain (145 to 509 residues) expressed in Baculovirus expression system by FRET-based Lanth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  420nMAssay Description:Binding affinity to human ALK1 by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  96nMAssay Description:Binding affinity to human ALK6 by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed