BDBM50464554 CHEMBL4288435::US10464907, Compound 14e::US10889552, Compound 14e

SMILES CN(Cc1ccc2OCOc2c1)C(=O)c1cc(Cl)c(O)cc1O

InChI Key InChIKey=AYAVCRCKKIWBAM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464554   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50464554(CHEMBL4288435 | US10464907, Compound 14e | US10889...)
Affinity DataIC50:  585nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50464554(CHEMBL4288435 | US10464907, Compound 14e | US10889...)
Affinity DataIC50:  585nMAssay Description:Endonuclease activity assays were carried out in Black Costar 96-well plates. Each well contained a total volume of 100 μL comprised of: buffer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Bovine)
Industry Academic Cooperation Foundation Keimyung University

US Patent
LigandPNGBDBM50464554(CHEMBL4288435 | US10464907, Compound 14e | US10889...)
Affinity DataIC50:  585nMAssay Description:Fluorescence polarization assay was performed to confirm the binding ability to the compound synthesized with HSP90 according the concentration. 1 M ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent